![]() In previously healthy young adults, self-poisoning is probably the reason for unexpected coma. If the patient is unable to provide accurate information (very young, unconscious, demented) circumstantial evidence may be important in establishing the diagnosis. History: In many cases, it is not difficult to make the correct diagnosis because a history of drug overdose or exposure to the toxic agent is provided by the patient, family members, witnesses or emergency services staff. Poisoning should be suspected in all cases of sudden, severe, and unexpected illness and in any patient who presents with multisystemic involvement. ![]() Diagnosis is based on the history, circumstantial evidence, a cluster of symptoms and signs, on the results of biochemical and toxicological analyses and ECG or X-ray abnormalities. Investigation of the Poisoned Patient - History Taking and Physical Examinationĭepartment of Clinical Toxicology, Jagiellonian University, Kraków, Polandīackground: Assessment of an acutely poisoned patient involves the taking of an appropriate history, assessment of the vital signs, level of consciousness, a physical examination, and requesting appropriate toxicological and non-toxicological investigations.
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